Winter Term 2019-20 / Cell Mol Neurosci


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 GUIDELINES  •  MODULE HANDBOOK 2019-20  •  IMPORTANT DATES  •  WEEK PLAN  •  EXAM SCHEDULE

Course title

Genetic and Molecular Basis of Neural Diseases I

Lecturer
Jucker, Gasser et al.
Credits
3.0
Course content / topics

Aging is the most important risk factor for neurodegenerative diseases and thus an understanding of the age-related neural changes is of fundamental importance. Cerebral proteopathy is a unifying term for neurodegenerative diseases in which proteins misfold and polymerize into aggregates that are resistant to clearance. Whether these protein aggregations are causative for the disease or are epiphenomena will be discussed for each disorder. This course emphasis on the molecular and cellular pathomechanisms of the most common dementias and other neurodegenerative disorders, especially Alzheimer’s and Parkinson’s disease. Other dementias covered in this lecture course are the heterogenous group of Frontotemporal Dementias, and the Prion diseases including Creutzfeldt-Jakob disease. Additional movement disorders discussed in this lecture series include Huntington’s disease and various ataxias. Finally, motor neuron disease such as Amyotrophic Lateral Sclerosis will be presented and the recent link to the pathogenesis of Frontotemporal Dementia highlighted.

Topics & Schedule

Day, time & location

Mon, 8.00-9.30 am, Seminar room 3.602B - DZNE